Endocrine Abstracts

Introduction: Papillary thyroid cancer (PTC) has an excellent prognosis in most cases with a 10-year survival rate of more than 95% but decreases drastically in cases of PTC iodine-refractory, in recurrent and/or metastatic disease. Tyrosine kinase inhibitors, such as lenvatinib or sorafenib, have been approved in such cases and in some cases are able to stabilize the disease and prolong survival. However, serious side effects have been reported such as fistula formation, blee...

Introduction: Many studies have shown that cigarette smoking exerts multiple effects on the thyroid gland. Smoking seems to induce changes in thyroid function tests, like a left-shift in serum TSH level that is more apparent in iodine-deficient subjects and increase in thyroid hormones. We describe the effect of an intensive thyroxine intravenous treatment in severe hypothyroid patients and the results depending on their smoking status.Material and metho...

Introduction: Bilateral sampling of the inferior petrosal sinuses is an accurate test to diagnose Cushing’s disease and distinguish it with the ectopic ACTH syndrome. The aim of the study was to review the petrosal sinus samplings carried out during last 10 years in our hospital.Methods and material: The medical histories of patients admitted for suspected Cushing’s disease in the last 10 years (from 2005 till 2015) were reviewed. There were se...